University of Gondar is one among the universities that have arisen to University level from the college of medicine and health sciences, with its current status and autonomy, in 2004. Accordingly, the Collage of Natural and Computational Sciences (CNCS), formerly called Faculty of Applied Natural Sciences and then Faculty of Natural and Computational Sciences, was one of the founding faculties at the inception of Gondar University College in 2003.
At the establishment, the faculty had only four under graduate fields of studies, namely, Applied Mathematics, Applied Physics, Applied Chemistry, and Applied Biology. Since then, the faculty has registered several achievements and there are vital landmarks in the history of the university. The collage has developed curricula for several new fields of studies, and has shouldered the responsibilities of institutional management.
Currently, the collage has reached 7 undergraduate Departments (Biology, Chemistry, Geology, Mathematics, Physics, Sport Sciences and Statistics) and 30 postgraduate programs (26 M.Sc. and 10 PhD programs). In addition, extension and summer in undergraduate and postgraduate programs are offered by most of the departments. Besides, the college members are engaged in researches, various community services and technology transfer activities.  Thus, to reach the community and tackle the problems, in the College, problem solving research activities, need based community services and enabling technology transfer are taking places.
The Collage also generates income through continuing education, short term trainings, laboratory and registrar services.